What is Bexsero?

Bexsero is a vaccine that protects against meningococcal group B disease, a serious bacterial infection that can cause meningitis and septicaemia. It has been used in the UK routine immunisation programme for babies since 2015 and has led to 75% reduction in MenB infections for vaccinated groups.

Does Bexsero protect against gonorrhoea too?

Not completely, but it can help.

Studies show that people who receive Bexsero are around 30–40% less likely to catch gonorrhoea compared with those who are not vaccinated.

This is because the bacteria that cause meningitis B (Neisseria meningitidis) and gonorrhoea (Neisseria gonorrhoeae) are closely related, and the vaccine stimulates antibodies that work against both.

Is Bexsero licensed for gonorrhoea?

No. Bexsero is officially licensed only for meningitis B. Using it to reduce gonorrhoea risk is considered “off-label.” Recent UK guidance (August 2025) from the Joint Committee on Vaccination and Immunisation (JCVI) has recommended a targeted programme as a starting point.

Who is being offered Bexsero for gonorrhoea protection?

In the UK, health experts now recommend offering it to people at higher risk of gonorrhoea, such as:

• Gay, bisexual, and other men who have sex with men (GBMSM)
• People who attend sexual health clinics regularly
• Those with multiple sexual partners

How is the Bexsero vaccine given, and what are the side effects?

The vaccine is usually given as two doses, at least 4 weeks apart (though sometimes up to six months apart). This can be done at our practice or your local sexual health clinic. It is a vaccine injection and is usually given in the upper arm.

Side effects include:

• Swelling, redness or tenderness at the injection site.
• Mild fever, nausea, headache or muscle aches (lasts 1-2 days)

Does the Bexsero vaccine replace condoms or STI testing?

No. The protection is only partial.  It takes at least two weeks from the second dose for the body to produce enough antibodies for a decent level of protection. The vaccine provides around 30-40% protection against gonorrhoea.

Therefore, you can still get gonorrhoea even after being vaccinated. Condoms, regular STI (sexually transmitted infection) checks, and safer sex practices remain very important.  We offer a wide range of sexual health services at Sloane Street Surgery, including STI screening, testing and treatment.

How long does protection from Bexsero last?

Current studies suggest protection may last a few years, but we don’t yet know the full picture. Research is ongoing to see whether booster doses might be needed.

Does Bexsero treat gonorrhoea if I already have it?

Unfortunately, no. The vaccine helps prevent future infections, but it cannot cure gonorrhoea. If you think you may have an STI, you still need to get tested and treated.

Why is this important?

• Gonorrhoea rates are rising in the UK and worldwide.
• The bacteria are becoming resistant to antibiotics, making treatment harder.
• Even partial protection from a vaccine could help reduce infections and slow resistance.

In summary

Bexsero will not replace condoms or testing, but it does offer extra protection. If you’re in a higher-risk group, you may be a candidate for the vaccine. This is available at Sloane Street Surgery or your local sexual health clinic.

Looking after your sexual health

Your sexual health is an important part of your overall well-being. We encourage all our sexually active patients to have regular STI screening, especially if you notice any symptoms or have any concerns. Early detection makes most STIs easily treatable and helps prevent complications.

We understand that conversations about sexual health can sometimes feel awkward – but they don’t have to be.

Our GPs are here to offer a safe, non-judgmental space where you can talk openly and get the care you need. Whether it is for routine screening or to discuss specific symptoms or risks, we are here to support you.

If you’d like to learn more or have questions about screening, please feel free to book an appointment with any of our GPs. Your health and comfort are our priority.

To book an appointment, call us on 0207 245 9333 or book online today.

 

References:

https://pmc.ncbi.nlm.nih.gov/articles/PMC4241781/

A guide to the Meningococcal B vaccine for protection against Gonorrhoea – GOV.UK